Superiority Hi! This is Monica from Shandong Huashang Chemical Co., Ltd, Welcome to my lookchem mall! Our company specializes in processing and selling chemical raw materials, our price is very competitive and our service is excellent. Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the
Hi! This is Monica from Shandong Huashang Chemical Co., Ltd, Welcome to my lookchem mall! Our company specializes in processing and selling chemical raw materials, our price is very competitive and our service is excellent.
Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
We adhere to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quality comes first, fair price, good sense of customer service and responsibility. in the future we will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
All we want is win-win situation. Send us your inquiries, you will find we are the best choie for you!
Product Description
Tacrolimus
Brief Description
CAS NO. 104987-11-3
M.F: C44H69NO12
M.W: 804.02
Competitive price with high quality
Conforms to BP/USP/EP/FCC
Specification
|
ITEM |
STANDARD |
|
M. Wt |
804.02 |
|
Formula |
C44H69NO12 |
|
Storage |
Store at -20°C |
|
Purity |
≥99% (HPLC) |
|
CAS Number |
104987-11-3 |
Details
Medical use
1. Organ transplantation
It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long-term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate, and IL-2 receptor inhibitors such as basiliximab. Dosages are titrated to target blood levels.
2. Ulcerative colitis
In recent years, tacrolimus has been used to suppress the inflammation associated with ulcerative colitis (UC), a form of inflammatory bowel disease. Although almost exclusively used in trial cases only, tacrolimus has shown to be significantly effective in the suppression of outbreaks of UC.
3. Skin
Tacrolimus 0.1% ointment
See also: Medications used in treatment of eczema
As an ointment, tacrolimus is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way to steroids, and is equally as effective as a mid-potency steroid. An important advantage of tacrolimus is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side effects.
It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids.[citation needed] Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face.
